Selected publications by topic
TFIIH and the CDK-activating kinase
Greber BJ# (2024)
High-resolution cryo-EM of a small protein complex: The structure of the human CDK-activating kinase.
Structure 32: 380-392, doi: 10.1016/j.str.2024.03.003. #corresponding author Link
Cushing VI, Koh AF, Feng J, Jurgaityte K, Bondke A, Kroll SHB, Barbazanges M, Scheiper B, Bahl AK, Barret AGM, Ali S#, Kotecha A#, Greber BJ# (2024).
High-resolution cryo-electron microscopy of the human CDK-activating kinase for structure-based drug design.
Nat. Commun. 15: 2265. #corresponding authors Link
bioRxiv, doi: 2023.04.07.536029. #corresponding authors Link
Greber BJ#, Perez-Bertoldi J M, Lim K, Iavarone AT, Nogales E# (2020).
The cryoelectron microscopy structure of the human CDK-activating kinase.
Proc. Natl. Acad. Sci. U.S.A. 549 (7672): 414-417. doi: 10.1073/pnas.2009627117 Epub 2020 Aug 27. #corresponding authors PubMed
bioRxiv, doi: 10.1101/2020.05.13.094755. Posted 2020 May 13. Link
Greber BJ, Toso DB, Fang J, Nogales E (2019).
The complete structure of the human TFIIH core complex.
eLife 8: e44771. Epub 2019 Mar 12. PubMed
bioRxiv, doi: 10.1101/507723. Posted 2019 Jan 5. Link
Greber BJ, Nguyen THD, Fang J, Afonine PV, Adams PD, Nogales E (2017).
The cryo-electron microscopy structure of human transcription factor IIH.
Nature 549 (7672): 414-417. Epub 2017 Sep 13. PubMed
Greber BJ# (2024)
High-resolution cryo-EM of a small protein complex: The structure of the human CDK-activating kinase.
Structure 32: 380-392, doi: 10.1016/j.str.2024.03.003. #corresponding author Link
Cushing VI, Koh AF, Feng J, Jurgaityte K, Bondke A, Kroll SHB, Barbazanges M, Scheiper B, Bahl AK, Barret AGM, Ali S#, Kotecha A#, Greber BJ# (2024).
High-resolution cryo-electron microscopy of the human CDK-activating kinase for structure-based drug design.
Nat. Commun. 15: 2265. #corresponding authors Link
bioRxiv, doi: 2023.04.07.536029. #corresponding authors Link
Greber BJ#, Perez-Bertoldi J M, Lim K, Iavarone AT, Nogales E# (2020).
The cryoelectron microscopy structure of the human CDK-activating kinase.
Proc. Natl. Acad. Sci. U.S.A. 549 (7672): 414-417. doi: 10.1073/pnas.2009627117 Epub 2020 Aug 27. #corresponding authors PubMed
bioRxiv, doi: 10.1101/2020.05.13.094755. Posted 2020 May 13. Link
Greber BJ, Toso DB, Fang J, Nogales E (2019).
The complete structure of the human TFIIH core complex.
eLife 8: e44771. Epub 2019 Mar 12. PubMed
bioRxiv, doi: 10.1101/507723. Posted 2019 Jan 5. Link
Greber BJ, Nguyen THD, Fang J, Afonine PV, Adams PD, Nogales E (2017).
The cryo-electron microscopy structure of human transcription factor IIH.
Nature 549 (7672): 414-417. Epub 2017 Sep 13. PubMed
Mitochondrial ribosomes
Greber BJ, Ban N (2016).
Structure and function of the mitochondrial ribosome.
Annual Review of Biochemistry 85 (1): 103-132. Epub 2016 Mar 24. PubMed
Greber BJ*, Bieri P*, Leibundgut M*, Leitner A, Aebersold R, Boehringer D, Ban N (2015).
The complete structure of the 55S mammalian mitochondrial ribosome.
Science 348 (6232): 303-308. Epub 2015 Apr 2. *equal contribution PubMed
Greber BJ*, Boehringer D*, Leibundgut M*, Bieri P, Leitner A, Schmitz N, Aebersold R, Ban N (2014).
The complete structure of the large subunit of the mammalian mitochondrial ribosome.
Nature 515 (7526): 283–286. Epub 2014 Oct 1. *equal contribution PubMed
Greber BJ*, Boehringer D*, Leitner A, Bieri P, Voigts-Hoffman F, Erzberger JP, Leibundgut M, Aebersold R, Ban N (2014).
Architecture of the large subunit of the mammalian mitochondrial ribosome.
Nature 505 (7484): 515–519. Epub 2013 Dec 22. *equal contribution PubMed F1000Prime
Greber BJ, Ban N (2016).
Structure and function of the mitochondrial ribosome.
Annual Review of Biochemistry 85 (1): 103-132. Epub 2016 Mar 24. PubMed
Greber BJ*, Bieri P*, Leibundgut M*, Leitner A, Aebersold R, Boehringer D, Ban N (2015).
The complete structure of the 55S mammalian mitochondrial ribosome.
Science 348 (6232): 303-308. Epub 2015 Apr 2. *equal contribution PubMed
Greber BJ*, Boehringer D*, Leibundgut M*, Bieri P, Leitner A, Schmitz N, Aebersold R, Ban N (2014).
The complete structure of the large subunit of the mammalian mitochondrial ribosome.
Nature 515 (7526): 283–286. Epub 2014 Oct 1. *equal contribution PubMed
Greber BJ*, Boehringer D*, Leitner A, Bieri P, Voigts-Hoffman F, Erzberger JP, Leibundgut M, Aebersold R, Ban N (2014).
Architecture of the large subunit of the mammalian mitochondrial ribosome.
Nature 505 (7484): 515–519. Epub 2013 Dec 22. *equal contribution PubMed F1000Prime
Ribosome assembly
Greber BJ (2016).
Mechanistic insight into eukaryotic 60S ribosomal subunit biogenesis by cryo-electron microscopy.
RNA 22 (11): 1643-1662. PubMed
Greber BJ*, Gerhardy S*, Leitner A, Leibundgut M, Salem M, Boehringer D, Leulliot N, Aebersold R, Panse VG, Ban N (2016).
Insertion of the biogenesis factor Rei1 probes the ribosomal tunnel during 60S maturation.
Cell 164 (1-2): 91-102. Epub 2015 Dec 17. *equal contribution PubMed
Greber BJ, Boehringer D, Montellese C, Ban N (2012).
Cryo-EM Structures of Arx1 and Maturation Factors Rei1 and Jjj1 Bound to the 60S Ribosomal Subunit.
Nat. Struct. Mol. Biol. 19 (12): 1228-33. Epub 2012 Nov 11. PubMed
Greber BJ (2016).
Mechanistic insight into eukaryotic 60S ribosomal subunit biogenesis by cryo-electron microscopy.
RNA 22 (11): 1643-1662. PubMed
Greber BJ*, Gerhardy S*, Leitner A, Leibundgut M, Salem M, Boehringer D, Leulliot N, Aebersold R, Panse VG, Ban N (2016).
Insertion of the biogenesis factor Rei1 probes the ribosomal tunnel during 60S maturation.
Cell 164 (1-2): 91-102. Epub 2015 Dec 17. *equal contribution PubMed
Greber BJ, Boehringer D, Montellese C, Ban N (2012).
Cryo-EM Structures of Arx1 and Maturation Factors Rei1 and Jjj1 Bound to the 60S Ribosomal Subunit.
Nat. Struct. Mol. Biol. 19 (12): 1228-33. Epub 2012 Nov 11. PubMed
